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Home / Peptide products / Catalog peptides / O (773 species) / Orexin /
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[Ala11,D-Leu15]-Orexin B (human)

Name
[Ala11,D-Leu15]-Orexin B (human)
Molecular structural formula
Purity
≥95%
CAS Number
532932-99-3
Formula
C120H206N44O35S
MW
2857.28
Target
others
Sequence
Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg- Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Sequence Shortening
RSGPPGLQGRAQRLLQASGNHAAGILTM-NH2
InChIKey
SURUUKNICBOUOQ-UBNRXWOCSA-N
References
[1]. Asahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Bioorg Med Chem Lett. 2003;13(1):111-113.
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Product details
Data download

[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM).